Serruys PW, Hara H, Onuma Y. Did the SYNTAX Score Pass the Test of Time? JACC Cardiovasc Interv. 2020 May 25;13(10):1207-1210. doi:10.1016/j.jcin.2020.03.040. PMID: 32438991.
Serruys PW, Chichareon P, Modolo R, Leaman DM, Reiber JHC, Emanuelsson H, Di Mario C, Pijls NHJ, Morel MA, Valgimigli M, Farooq V, van Klaveren D, Capodanno D, Andreini D, Bourantas CV, Davies J, Banning AP, Escaned J, Piek JJ, Echavarría-Pinto M, Taylor CA, Thomsen B, Collet C, Pompilio G, Bartorelli AL, Glocker B, Dressler O, Stone GW, Onuma Y. The SYNTAX score on its way out or … towards artificial intelligence: part I. EuroIntervention. 2020 May 20;16(1):44-59. doi: 10.4244/EIJ-D-19-00543A. PMID: 31651399.
Serruys PW, Chichareon P, Modolo R, Leaman DM, Reiber JHC, Emanuelsson H, Di Mario C, Pijls NHJ, Morel MA, Valgimigli M, Farooq V, van Klaveren D, Capodanno D, Andreini D, Bourantas CV, Davies J, Banning AP, Escaned J, Piek JJ, Echavarría-Pinto M, Taylor CA, Thomsen B, Collet C, Pompilio G, Bartorelli AL, Glocker B, Dressler O, Stone GW, Onuma Y. The SYNTAX score on its way out or … towards artificial intelligence: part II. EuroIntervention. 2020 May 20;16(1):60-75. doi: 10.4244/EIJ-D-19-00543B. PMID: 31651398.
Mancone M, Cavalcante R, Modolo R, Falcone M, Biondi-Zoccai G, Frati G, Spitzer E, Benedetto U, Blackstone EH, Onuma Y, van Geuns RM, Diletti R, Serruys PW. Major infections after bypass surgery and stenting for multivessel coronary disease in the randomised SYNTAX trial. EuroIntervention. 2020 Apr 17;15(17):1520-1526. doi: 10.4244/EIJ-D-19-00208. PMID: 31289019.
Hara H, Kogame N, Takahashi K, Modolo R, Chichareon P, Tomaniak M, Ono M, Kawashima H, Gao C, Wang R, Valkov VD, Vom Dahl J, Steinwender C, Geisler T, Lemos Neto PA, Macaya Miguel C, Garg S, Jüni P, Hamm C, Steg PG, Valgimigli M, Vranckx P, Windecker S, Farooq V, Onuma Y, Serruys PW; GLOBAL LEADERS Trial Investigators. Usefulness of the updated logistic clinical SYNTAX score after percutaneous coronary intervention in patients with prior coronary artery bypass graft surgery: Insights from the GLOBAL LEADERS trial. Catheter Cardiovasc Interv. 2020 Apr 15. doi: 10.1002/ccd.28898. Epub ahead of print. PMID: 32294317.
Takahashi K, Thuijs DJFM, Hara H, Wang R, Mohr FW, Morice MC, Holmes DR Jr, Kappetein AP, Head SJ, Onuma Y, Serruys PW. Impact of the CABG SYNTAX Score on 10-year All-cause Death: Insights from the SYNTAX Extended Survival Study. EuroIntervention. 2020 Apr 14:EIJ-D-20-00170. doi: 10.4244/EIJ-D-20-00170. Epub ahead of print. PMID: 32287035.
Modolo R, Chichareon P, van Klaveren D, Dressler O, Zhang Y, Sabik JF, Onuma Y, Kappetein AP, Stone GW, Serruys PW. Impact of non-respect of SYNTAX score II recommendation for surgery in patients with left main coronary artery disease treated by percutaneous coronary intervention: an EXCEL substudy. Eur J Cardiothorac Surg. 2020 Apr 1;57(4):676-683. doi: 10.1093/ejcts/ezz274. PMID: 31620778.
Andreini D, Modolo R, Katagiri Y, Mushtaq S, Sonck J, Collet C, De Martini S, Roberto M, Tanaka K, Miyazaki Y, Czapla J, Schoors D, Plass A, Maisano F, Kaufmann P, Orry X, Metzdorf PA, Folliguet T, Färber G, Diamantis I, Schönweiß M, Bonalumi G, Guglielmo M, Ferrari C, Olivares P, Cavallotti L, Leal I, Lindeboom W, Onuma Y, Serruys PW, Bartorelli AL; SYNTAX III REVOLUTION Investigators. Impact of Fractional Flow Reserve Derived From Coronary Computed Tomography Angiography on Heart Team Treatment Decision-Making in Patients With Multivessel Coronary Artery Disease: Insights From the SYNTAX III REVOLUTION Trial. Circ Cardiovasc Interv. 2019 Dec;12(12):e007607. doi: 10.1161/CIRCINTERVENTIONS.118.007607. Epub 2019 Dec 13. PMID: 31833413.
Kogame N, Takahashi K, Tomaniak M, Chichareon P, Modolo R, Chang CC, Komiyama H, Katagiri Y, Asano T, Stables R, Fath-Ordoubadi F, Walsh S, Sabaté M, Davies JE, Piek JJ, van Geuns RJ, Reiber JHC, Banning AP, Escaned J, Farooq V, Serruys PW, Onuma Y. Clinical Implication of Quantitative Flow Ratio After Percutaneous Coronary Intervention for 3-Vessel Disease. JACC Cardiovasc Interv. 2019 Oct 28;12(20):2064-2075. doi: 10.1016/j.jcin.2019.08.009. Epub 2019 Sep 25. PMID: 31563682.
Thuijs DJFM, Kappetein AP, Serruys PW, Mohr FW, Morice MC, Mack MJ, Holmes DR Jr, Curzen N, Davierwala P, Noack T, Milojevic M, Dawkins KD, da Costa BR, Jüni P, Head SJ; SYNTAX Extended Survival Investigators. Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three- vessel or left main coronary artery disease: 10-year follow-up of the multicentre randomised controlled SYNTAX trial. Lancet. 2019 Oct 12;394(10206):1325-1334. doi: 10.1016/S0140-6736(19)31997-X. Epub 2019 Sep 2. Erratum in: Lancet. 2020 Mar 14;395(10227):870. PMID: 31488373.
Shlofmitz E, Généreux P, Chen S, Dressler O, Ben-Yehuda O, Morice MC, Puskas JD, Taggart DP, Kandzari DE, Crowley A, Redfors B, Mehdipoor G, Kappetein AP, Sabik JF 3rd, Serruys PW, Stone GW. Left Main Coronary Artery Disease Revascularization According to the SYNTAX Score. Circ Cardiovasc Interv. 2019 Sep;12(9):e008007. doi: 10.1161/CIRCINTERVENTIONS.118.008007. Epub 2019 Sep 9. PMID: 31495220.
Modolo R, Kogame N, Komiyama H, Chichareon P, de Vries T, Tomaniak M, Chang CC, Takahashi K, Walsh S, Lesiak M, Moreno R, Farrooq V, Escaned J, Banning A, Onuma Y, Serruys PW. Two years clinical outcomes with the state-of-the-art PCI for the treatment of bifurcation lesions: A sub-analysis of the SYNTAX II study. Catheter Cardiovasc Interv. 2020 Jul;96(1):10-17. doi: 10.1002/ccd.28422. Epub 2019 Aug 12. PMID: 31402574.
Chichareon P, Onuma Y, van Klaveren D, Modolo R, Kogame N, Takahashi K, Chang CC, Tomaniak M, Asano T, Katagiri Y, van Geuns RM, Bolognese L, Tumscitz C, Vrolix M, Petrov I, Garg S, Naber CK, Sabaté M, Iqbal J, Wykrzykowska JJ, Piek JJ, Spitzer E, Jüni P, Hamm C, Steg PG, Valgimigli M, Vranckx P, Windecker S, Serruys PW. Validation of the updated logistic clinical SYNTAX score for all- cause mortality in the GLOBAL LEADERS trial. EuroIntervention. 2019 Aug 9;15(6):e539-e546. doi: 10.4244/EIJ-D-19-00184. PMID: 31217143.
Serruys PW, Kogame N, Katagiri Y, Modolo R, Buszman PE, Íñiguez-Romo A, Goicolea J, Hildick-Smith D, Ochala A, Dudek D, Piek JJ, Wykrzykowska JJ, Escaned J, Banning AP, Farooq V, Onuma Y. Clinical outcomes of state-of-the-art percutaneous coronary revascularisation in patients with three-vessel disease: two-year follow-up of the SYNTAX II study. EuroIntervention. 2019 Jun 12;15(3):e244-e252. doi: 10.4244/EIJ-D-18-00980. PMID: 30636684.
Fujino A, Kadohira T, Redfors B, Maehara A, Serruys PW, Mintz GS, Stone GW, Généreux P. Significant association among residual SYNTAX score, non-culprit major adverse cardiac events, and greyscale and virtual histology intravascular ultrasound findings: a substudy from the PROSPECT study. EuroIntervention. 2019 Mar 20;14(16):1676-1684. doi: 10.4244/EIJ-D-18-00681. PMID: 30561370.
Sonck J, Miyazaki Y, Collet C, Onuma Y, Asano T, Takahashi K, Kogame N, Katagiri Y, Modolo R, Serruys PW, Bartorelli AL, Andreini D, Doenst T, Maureira JP, Plass A, La Meir M, Pompillio G. Feasibility of planning coronary artery bypass grafting based only on coronary computed tomography angiography and CT- derived fractional flow reserve: a pilot survey of the surgeons involved in the randomized SYNTAX III Revolution trial. Interact Cardiovasc Thorac Surg. 2019 Mar 18:ivz046. doi: 10.1093/icvts/ivz046. Epub ahead of print. PMID: 30887024.
Asano T, Katagiri Y, Chang CC, Kogame N, Chichareon P, Takahashi K, Modolo R, Tenekecioglu E, Collet C, Jonker H, Appleby C, Zaman A, van Mieghem N, Uren N, Zueco J, Piek JJ, Reiber JHC, Farooq V, Escaned J, Banning AP, Serruys PW, Onuma Y. Angiography-Derived Fractional Flow Reserve in the SYNTAX II Trial: Feasibility, Diagnostic Performance of Quantitative Flow Ratio, and Clinical Prognostic Value of Functional SYNTAX Score Derived From Quantitative Flow Ratio in Patients With 3-Vessel Disease. JACC Cardiovasc Interv. 2019 Feb 11;12(3):259-270. doi: 10.1016/j.jcin.2018.09.023. PMID: 30409759.
Katagiri Y, De Maria GL, Kogame N, Chichareon P, Takahashi K, Chang CC, Modolo R, Walsh S, Sabate M, Davies J, Lesiak M, Moreno R, Cruz-Gonzalez I, West NEJ, Piek JJ, Wykrzykowska JJ, Farooq V, Escaned J, Banning AP, Onuma Y, Serruys PW. Impact of post-procedural minimal stent area on 2-year clinical outcomes in the SYNTAX II trial. Catheter Cardiovasc Interv. 2019 Mar 1;93(4):E225-E234. doi: 10.1002/ccd.28105. Epub 2019 Jan 31. PMID: 30702187.
Vroegindewey MM, Schuurman AS, Kardys I, Anroedh SS, Oemrawsingh RM, Ligthart J, Garcia-Garcia HM, van Geuns RM, Regar E, Van Mieghem NM, Serruys PW, Boersma E, Akkerhuis M. SYNTAX score in relation to intravascular ultrasound and near-infrared spectroscopy for the assessment of atherosclerotic burden in patients with coronary artery disease. EuroIntervention. 2019 Jan 20;14(13):1408-1415. doi: 10.4244/EIJ-D-17-00827. PMID: 29537372.
Collet C, Onuma Y, Andreini D, Sonck J, Pompilio G, Mushtaq S, La Meir M, Miyazaki Y, de Mey J, Gaemperli O, Ouda A, Maureira JP, Mandry D, Camenzind E, Macron L, Doenst T, Teichgräber U, Sigusch H, Asano T, Katagiri Y, Morel MA, Lindeboom W, Pontone G, Lüscher TF, Bartorelli AL, Serruys PW. Coronary computed tomography angiography for heart team decision-making in multivessel coronary artery disease. Eur Heart J. 2018 Nov 1;39(41):3689-3698. doi: 10.1093/eurheartj/ehy581. PMID: 30312411; PMCID: PMC6241466.
Vroegindewey MM, Schuurman AS, Oemrawsingh RM, van Geuns RJ, Kardys I, Ligthart J, Daemen J, Boersma E, Serruys PW, Akkerhuis KM. SYNTAX score II predicts long-term mortality in patients with one- or two-vessel disease. PLoS One. 2018 Jul 2;13(7):e0200076. doi: 10.1371/journal.pone.0200076. PMID: 29965993; PMCID: PMC6028142.
Modolo R, Collet C, Onuma Y, Serruys PW. SYNTAX II and SYNTAX III trials: what is the take home message for surgeons? Ann Cardiothorac Surg. 2018 Jul;7(4):470-482. doi: 10.21037/acs.2018.07.02. PMID: 30094211; PMCID: PMC6082789.
Collet C, Miyazaki Y, Ryan N, Asano T, Tenekecioglu E, Sonck J, Andreini D, Sabate M, Brugaletta S, Stables RH, Bartorelli A, de Winter RJ, Katagiri Y, Chichareon P, De Maria GL, Suwannasom P, Cavalcante R, Jonker H, Morel MA, Cosyns B, Kappetein AP, Taggart DT, Farooq V, Escaned J, Banning A, Onuma Y, Serruys PW. Fractional Flow Reserve Derived From Computed Tomographic Angiography in Patients With Multivessel CAD. J Am Coll Cardiol. 2018 Jun 19;71(24):2756-2769. doi: 10.1016/j.jacc.2018.02.053. Epub 2018 May 22. PMID: 29802016.
Milojevic M, Head SJ, Mack MJ, Mohr FW, Morice MC, Dawkins KD, Holmes DR Jr, Serruys PW, Kappetein AP. The impact of chronic kidney disease on outcomes following percutaneous coronary intervention versus coronary artery bypass grafting in patients with complex coronary artery disease: five-year follow-up of the SYNTAX trial. EuroIntervention. 2018 May 20;14(1):102-111. doi: 10.4244/EIJ-D-17-00620. PMID: 29155387.
Escaned J, Collet C, Ryan N, De Maria GL, Walsh S, Sabate M, Davies J, Lesiak M, Moreno R, Cruz-Gonzalez I, Hoole SP, Ej West N, Piek JJ, Zaman A, Fath- Ordoubadi F, Stables RH, Appleby C, van Mieghem N, van Geuns RJ, Uren N, Zueco J, Buszman P, Iñiguez A, Goicolea J, Hildick-Smith D, Ochala A, Dudek D, Hanratty C, Cavalcante R, Kappetein AP, Taggart DP, van Es GA, Morel MA, de Vries T, Onuma Y, Farooq V, Serruys PW, Banning AP. Clinical outcomes of state- of-the-art percutaneous coronary revascularization in patients with de novo three vessel disease: 1-year results of the SYNTAX II study. Eur Heart J. 2017 Nov 7;38(42):3124-3134. doi: 10.1093/eurheartj/ehx512. Erratum in: Eur Heart J. 2018 May 7;39(18):1619. PMID: 29020367; PMCID: PMC5837643.
Roy AK, Chevalier B, Lefèvre T, Louvard Y, Segurado R, Sawaya F, Spaziano M, Neylon A, Serruys PA, Dawkins KD, Kappetein AP, Mohr FW, Colombo A, Feldman T, Morice MC. Does geographical variability influence five-year MACCE rates in the multicentre SYNTAX revascularisation trial? EuroIntervention. 2017 Sep 20;13(7):828-834. doi: 10.4244/EIJ-D-16-00991. PMID: 28320685.
Milojevic M, Head SJ, Mack MJ, Mohr FW, Morice MC, Dawkins KD, Holmes DR Jr, Serruys PW, Kappetein AP. Influence of practice patterns on outcome among countries enrolled in the SYNTAX trial: 5-year results between percutaneous coronary intervention and coronary artery bypass grafting. Eur J Cardiothorac Surg. 2017 Sep 1;52(3):445-453. doi: 10.1093/ejcts/ezx104. PMID: 28520861.
Ahn JM, Park DW, Lee CW, Chang M, Cavalcante R, Sotomi Y, Onuma Y, Tenekecioglu E, Han M, Lee PH, Kang SJ, Lee SW, Kim YH, Park SW, Serruys PW, Park SJ. Comparison of Stenting Versus Bypass Surgery According to the Completeness of Revascularization in Severe Coronary Artery Disease: Patient- Level Pooled Analysis of the SYNTAX, PRECOMBAT, and BEST Trials. JACC Cardiovasc Interv. 2017 Jul 24;10(14):1415-1424. doi: 10.1016/j.jcin.2017.04.037. PMID: 28728654.
Cavalcante R, Sotomi Y, Mancone M, Whan Lee C, Ahn JM, Onuma Y, Lemos PA, van Geuns RJ, Park SJ, Serruys PW. Impact of the SYNTAX scores I and II in patients with diabetes and multivessel coronary disease: a pooled analysis of patient level data from the SYNTAX, PRECOMBAT, and BEST trials. Eur Heart J. 2017 Jul 1;38(25):1969-1977. doi: 10.1093/eurheartj/ehx138. PMID: 28431047.
Milojevic M, Head SJ, Andrinopoulou ER, Serruys PW, Mohr FW, Tijssen JG, Kappetein AP. Hierarchical testing of composite endpoints: applying the win ratio to percutaneous coronary intervention versus coronary artery bypass grafting in the SYNTAX trial. EuroIntervention. 2017 May 15;13(1):106-114. doi: 10.4244/EIJ-D-16-00745. PMID: 28134125.
Sotomi Y, Onuma Y, Cavalcante R, Ahn JM, Lee CW, van Klaveren D, de Winter RJ, Wykrzykowska JJ, Farooq V, Morice MC, Steyerberg EW, Park SJ, Serruys PW. Geographical Difference of the Interaction of Sex With Treatment Strategy in Patients With Multivessel Disease and Left Main Disease: A Meta-Analysis From SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery), PRECOMBAT (Bypass Surgery Versus Angioplasty Using Sirolimus-Eluting Stent in Patients With Left Main Coronary Artery Disease), and BEST (Bypass Surgery and Everolimus-Eluting Stent Implantation in the Treatment of Patients With Multivessel Coronary Artery Disease) Randomized Controlled Trials. Circ Cardiovasc Interv. 2017 May;10(5):e005027. doi: 10.1161/CIRCINTERVENTIONS.117.005027. PMID: 28495897.
Collet C, Onuma Y, Miyazaki Y, Morel MA, Serruys PW. Integration of non- invasive functional assessments with anatomical risk stratification in complex coronary artery disease: the non-invasive functional SYNTAX score. Cardiovasc Diagn Ther. 2017 Apr;7(2):151-158. doi: 10.21037/cdt.2017.03.19. PMID: 28540210; PMCID: PMC5422844.
Cavalcante R, Onuma Y, Sotomi Y, Collet C, Thomsen B, Rogers C, Zeng Y, Tenekecioglu E, Asano T, Miyasaki Y, Abdelghani M, Morel MA, Serruys PW. Non- invasive Heart Team assessment of multivessel coronary disease with coronary computed tomography angiography based on SYNTAX score II treatment recommendations: design and rationale of the randomised SYNTAX III Revolution trial. EuroIntervention. 2017 Mar 20;12(16):2001-2008. doi: 10.4244/EIJ-D-16-00612. PMID: 27973335.
Stanetic BM, Ostojic M, Campos CM, Marinkovic J, Farooq V, Kovacevic- Preradovic T, Huber K, Serruys PW. ApPropriateness of myocaRdial RevascularizatiOn assessed by the SYNTAX score II in a coUntry without cardiac Surgery faciliTies; PROUST study. Int J Cardiol. 2017 Jan 15;227:478-484. doi: 10.1016/j.ijcard.2016.11.001. Epub 2016 Nov 3. PMID: 27825727.
Farooq V, van Klaveren D, Steyerberg EW, Meliga E, Vergouwe Y, Chieffo A, Kappetein AP, Colombo A, Holmes DR Jr, Mack M, Feldman T, Morice MC, Ståhle E, Onuma Y, Morel MA, Garcia-Garcia HM, van Es GA, Dawkins KD, Mohr FW, Serruys PW. Anatomical and clinical characteristics to guide decision making between coronary artery bypass surgery and percutaneous coronary intervention for individual patients: development and validation of SYNTAX score II. Lancet. 2013 Feb 23;381(9867):639-50. doi: 10.1016/S0140-6736(13)60108-7. PMID: 23439103.
Sianos G, Morel MA, Kappetein AP, Morice MC, Colombo A, Dawkins K, van den Brand M, Van Dyck N, Russell ME, Mohr FW, Serruys PW. The SYNTAX Score: an angiographic tool grading the complexity of coronary artery disease. EuroIntervention. 2005 Aug;1(2):219-27. PMID: 19758907.